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LIFEx v1.2 is now available. Many features are already included in this release. 


The software is written in Java and does not use any commercial libraries. LIFEx is dedicated to researchers, radiologists, nuclear medicine physicians and oncologists and includes three operation modes:

  • 1) “validated”: simplified user interface displaying conventional indices (e.g. SUV, Metabolic Volume and Total Lesion Glycolysis in FDG PET) as well as 6 textural indices calculated with default settings that have been thoroughly validated and proved as robust in previous publications;
  • 2) “intermediate”, offering 6 additional histogram and shape indices ;
  • 3) “advanced”, giving access to 37 histogram, texture and shape indices in addition to conventional indices and in which users can change calculation options (e.g. resampling method and number of grey levels for texture analysis).

LIFEx reads DICOM images locally or over a network using a DICOM browser, is compatible with Osirix and includes a powerful 3D reconstruction-based slice viewer. Volume of interest (VOI) can be either imported from previously created files or drawn and manipulated using LIFEx. Results are exported in Excel format files. LIFEx runs on Windows, MacOs and Linux. It is distributed with examples and includes a tutorial. User support is offered for the “validated” mode. Users can optionally contribute to the gathering of index values in different tissue types and different images as a public data bank of reference values is currently being built and integrated to the software for assisting the users with the interpretation of their results.

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