LIFEx - LIFEx

LIFEx v25.06.1 now available

LIFEx reads DICOM images locally or over a network using a DICOM browser and includes a powerful 3D reconstruction-based slice viewer. Volume of interest (VOI) can be either imported from previously created files or drawn and manipulated using LIFEx. Results are exported in Excel format files. LIFEx runs on Windows, MacOs and Linux. It is distributed with examples and includes a tutorial. User support is offered. Users can optionally contribute to the gathering of index values in different tissue types and different images as a public data bank of reference values is currently being built and integrated to the software for assisting the users with the interpretation of their results.

Download here : Download

LIFEx, Cancer Research 2018

LIFEx: a freeware for radiomic feature calculation in multimodality imaging to accelerate advances in the characterization of tumor heterogeneity

C Nioche, F Orlhac, S Boughdad, S Reuzé, J Goya-Outi, C Robert, C Pellot-Barakat, M Soussan, F Frouin, and I Buvat. LIFEx: a freeware for radiomic feature calculation in multimodality imaging to accelerate advances in the characterization of tumor heterogeneity. Cancer Research 2018; 78(16):4786-4789

LIFExAnalytics

1018 publications (weekly update):

Evolution of the publications:
(from PubMed)
2016: 2 publications
2017: 5 publications
2018: 26 publications
2019: 50 publications
2020: 95 publications
2021: 157 publications
2022: 166 publications
2023: 175 publications
2024: 220 publications
2025: 122 publications
(2025 in progress)

10194 user accounts (live update):

Evolution of the accounts:
(from our site web)
2016: #160 (0.4 account/day)
2017: #323 (0.9 account/day)
2018: #802 (2.2 accounts/day)
2019: #1181 (3.2 accounts/day)
2020: #1358 (3.7 accounts/day)
2021: #1327 (3.6 accounts/day)
2022: #1155 (3.2 accounts/day)
2023: #1272 (3.5 accounts/day)
2024: #1535 (4.2 accounts/day)
2025: #1081 (4.1 accounts/day)
(2025 in progress)

Location of user cities (monthly update):

Screenshot MIP demos


MIP PET/CT	MIP PET/ROI	MIP PET

Popular Features 2025

reads nifti (.nii), ecat (.v), DICOM / RTSTRUCT (.dcm) files, and many others...
creates 2D or 3D ROI
analyses 306 histogram-based, image feature and mtv indices
complies with the Image biomarker standardisation initiative (IBSI)
calculates total metabolic volume in PET
MIP visualization
writes results in Comma Separated Value (.csv)
numerous publications (549 at 2023-04)
large community of users (more than 6700 users)

Meet us

You can always meet us at:

2026 SNMMI Annual Meeting, Los Angeles, USA from May 30 - June 2, 2026
EANM'25, Annual Congress of the European Association of Nuclear Medicine, October 4 – 8, 2025, International Barcelona Convention Center (CCIB)
at Institut Curie Centre De Recherche, Centre Universitaire, Bâtiment 101B, Rue Henri Becquerel, 91898 ORSAY CEDEX, 91400, Orsay, France

We are also attending many scientific meetings and conferences where you can meet us.

ESTRO meeting 2026, 15 May 2026 - 19 May 2026 Stockholm, Sweden

If you want to meet us there, please send us an email at This email address is being protected from spambots. You need JavaScript enabled to view it..