# Overview

The libraries used by LIFEx and included in the package are as follows (you do NOT have anything to install except the single LIFEx package):

<**************** LIFEx public version 4.70 *****************v
version 4.70 - Sat Feb 16 18pm CEST 2019

What's new in (feature release) LIFEx 4.70?
- fixed: slice thickness on Biograph_mMR (Siemens)
- fixed (texture protocol): RIM index: proper units (mL and #vx) assigned in excel file
- fixed (texture protocol): RIM index on some extreme anysotropic voxels
- fixed (texture protocol): RIM index on more than one ROI
- fixed: on mac only, wheel rotation is good direction when 2 finger shift on trackpad (downgrade on jdk1.8.0_144 version)
- thresholding at 40% (and by extension at n%) allowed on the time series. Note that the activated series and the activated time t are defined as reference for the calculation of the maximum value from which the 40% (respectively n% value) is calculated
- added: image number unit (in #) on X axis (in addition to have sec, min, h units)
- fixed: inopportune flash on MIP movie


pre><**************** LIFEx public version 4.64 *****************
version 4.64 - Tue Feb 7 18pm CEST 2019
What's new in (feature release) LIFEx 4.64?
- updated: memory is better used when launching the application (linux all available memory without buff/cache is used)
- fixed: slice thickness on some CT scan

**************** LIFEx public version 4.62 *****************version 4.62 - Monday Feb 4 10am CEST 2019
What's new in (feature release) LIFEx 4.62?- fixed: change in the display of the cursor coordinates
- fixed: sorting the series when more than one series is loaded (sorting criterion is « acquisition number » dicom field)
- fixed (texture protocol): Automatic adjustment of relative/absolute intensity resampling menu as a function of the settings already filled


**************** LIFEx public version 4.60 *****************version 4.60 - Wednesday Jan 30 07pm CEST 2019


**************** LIFEx public version 4.00 *****************version 4.00 - Mon Apr 23 12:00:00 CEST 2018What's new in LIFEx 4.00?Main:- save dynamic series in DICOM format- directory in which data are saved can be changed by the user in preference frame- maps of GLCM features are now available- "diagnosis protocol" has been renamed "Viewer protocol"- increase in performance when calculating Texture GLCM matrixMajor bug fixes:- patient position corrected in dynamic time-seriesMinor bug fixes:- correction of timing value (msec) of the last time point in dynamic series- correction of min and max value units in graph - MTV: click & draw tool action now updates the MTV value- hide circle2D and circle3D when mouse cursor exits frame

RESEARCH USER LICENSE AGREEMENT FOR LIFEx SOFTWARE

USE OF THE LIFEx SOFTWARE IS SUBJECT TO THE FOLLOWING TERMS AND CONDITIONS.  IF YOU DO NOT ACCEPT THESE TERMS AND CONDITIONS, DO NOT DOWNLOAD THE SOFTWARE.

NON-PROFESSIONAL USERS ARE NOTIFIED THAT THE SOFTWARE AND THE RISKS INHERENT TO ITS USE, MODIFICATION AND/OR DEVELOPMENT AND REPRODUCTION ARE NOT COVERED BY ANY WARRANTY ON THE PART OF THE CEA. IT IS HIGHLY RECOMMENDED THAT YOU ONLY LOAD AND/OR USE THE SOFTWARE IF YOU HAVE SPECIALIZED IN-DEPTH INFORMATION TECHNOLOGY KNOW-HOW.

THE COMMISSARIAT A L’ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FRENCH ATOMIC ENERGY AGENCY), a public scientific, technical and industrial establishment, having its registered office at 25 rue Leblanc – bâtiment le Ponant D – 75015 Paris cedex, hereinafter referred to as “CEA”, hereby licenses the right to use the LIFEx software as per the terms and conditions set out below.

This license is granted to the natural or legal person – hereinafter the “Licensee” – having completed the application form and loaded the Software.

## Introduction

Texture analysis is gaining considerable interest in medical imaging, in particular to identify parameters that might characterize tumor heterogeneity. We developed an easy-to-use freeware enabling calculation of a broad range of conventional, textural and shape indices from PET, MR, US and CT images.

The software is written in Java and does not rely on any commercial libraries. LIFEx is dedicated to researchers, radiologists, nuclear medicine physicians and oncologists that giving access to 42 histogram, textural and shape indices in addition to conventional indices and where users can change calculation options (e.g. resampling method and number of grey levels for textural analysis).