Before asking questions or reporting problems to the contact address, please make sure your question has not been answered in the past.
Is LIFEx a free software?
Yes, it is free.
How can I download it?
Please see the download page.
Which system for LIFEX run on?
The following OS are supported: MacOs (El Capitan, Maverick, Sierra), Windows (7, 10), Linux (Fedora, RedHat, Ubuntu, Debian, Mint). No conflicts between system libraries and those of the binary packages exist.
I have installed an old version, can I reinstall over it without removing the previous version?
Yes you can. But if you run into problems, remove the old version(s) installed.
I get a warning from my antivirus software. Can I proceed with the use of the software safely?
Yes you can. Depending on your antivirus software, you may get an antivirus warning when installing LIFEx. For instance, Kapersky EndPoint Security 10 for windows detects an PDM:Trojan.Win32.Generic. See: http://support.kaspersky.com/fr/faq/?qid=208282629
Each and every version of LIFEx is carefully checked for any viral contamination and you can install it without any risk. You can disconnect your antivirus software during the installation to avoid that problem.
LIFEx can’t be opened because it is from an unidentified developer. Your security preferences only allow you to run applications from the Mac App Store and from identified developers ?
Two options to solve it:
- Right-click (or control-click) LIFEx icon and choose “Open”
- Click the “Open” button at the next dialog warning to launch the app anyway
- Launch System Preferences from the Apple menu
- Choose “Security & Privacy” and then click the “General” tab, followed by clicking the lock icon in the corner to unlock the settings
- Look for “Allow applications downloaded from:” and choose “Anywhere”
- Accept the security warning and allow
You can now launch any app from any location or developer
What is the ideal solution between the absolute or relative resampling in PET ?
In PET images, we do not recommend to use the relative resampling. As explained in https://www.ncbi.nlm.nih.gov/pubmed/26669541, relative resampling induces a high correlation between texture indices and metabolic volume, and we proposed to use the absolute resampling instead. In PET, we resample with 64 number of grey levels (size bin equals to 0.3) between 0 and 20 SUV units (because this is the standard range of SUVs in oncology with FDG). We think the same effect is observed in CT images, but if using the absolute resampling (which we recommend), you have to set yourself the range of HU and the number of bins (or bin size) for your data, as a function of the data content. Basically, the bin size has to be set as a function of the meaning of HU difference. If a HU difference of 10 does not mean much, then the bin size could be set to 10 for instance, using a smaller value is useless, and a range of HU between -1000HU and 3000HU for example (including all HU possible variations).
What is the ideal solution between the absolute or relative resampling in MR ?
In MR, the impact of different resampling schemes has been studied in http://iopscience.iop.org/article/10.1088/1361-6560/aabd21. Based on that paper, we recommend using a fixed bin width, which corresponds to absolute resampling.
In PET, the DICOM fields that have to be properly filled for correct SUV correction are:
DICOM fields to SUV conversion :
(0008,0032) TM #6  Acquisition Time
(0010,1020) DS #6  Patient’s Size
(0018,1074) DS #10  Radionuclide Total Dose
(0018,1075) DS #12  Half Life
(0018,1072) TM #6  Radiopharmaceutical Start Time
(0054,1001) CS #4  Units
(0028,1052) DS #2  Rescale Intercept
(0028,1053) DS #8  Rescale Slope
How to cite LIFEx?
Please see the How to cite LIFEx? page.