## Conventional Indices

CONV_SUVmin reflects the minimum Standardized Uptake Value (SUV) in the Volume of Interest.

CONV\_SUVmin=\min_{i}SUV_i

CONV_SUVmean reflects the average SUV in the Volume of Interest.

CONV\_SUVmean=\frac{1}{N}\sum_{i}SUV_i

CONV_SUVmax reflects the maximum SUV in the Volume of Interest.

CONV\_SUVmax=\max_{i}SUV_i

CONV_SUVpeak reflects the mean SUV in a sphere with a volume of ~0.5 or ~1 mL and located so that the average value in the VOI is maximum.

CONV_TLG (mL) is the Total Lesion Glycolysis defined as the product of $$SUVmean$$ by $$Volume$$ in mL. [LARSON 1999]

CONV\_SUVmean=V \cdot \frac{1}{N}\sum_{i}SUV_i

CONV_RIM
is the envelope Intensity Mean CONV_RIM_mean" of successive layers of voxels from the outside of the region to the inside. Each layer is 1 voxel thick. These envelopes are getting smaller and smaller (3D erosion of 1 voxel) up to the center of the ROI.

Other statistics are extracted from these envelopes, in particular:

• CONV_RIM_min: minimum value of voxel values from the envelopes
• CONV_RIM_stdev: standard deviation value of voxel values from the envelopes
• CONV_RIM_max: maximum value of voxel values from the envelopes
• CONV_RIM_Volume (mL): volume in millilitre unit of all voxels from the envelopes
• CONV_RIM_Volume (vx): volume in voxel unit of all voxels from the envelopes
• CONV_RIM_sum: sum of voxel values from the envelopes

Example of results for 6 envelopes:

• CONV_RIM_mean = 1.2684131|1.2192162|1.2974288|1.3191646|1.271777|1.226076|

The first value 1.2684131 is SUV_mean (if SUV is unit of voxel value), of the 1-voxel thick envelope of the ROI, 1.2192162 the mean of the envelope after an erosion of 1 voxel, 1.226076 the mean of the smallest envelope (center of ROI).